Christina Applegate has opened up about the pain she experiences from multiple sclerosis.
According to the National Institute of Neurological Disorders and Stroke, Multiple sclerosis is an autoimmune condition where the body attacks myelin, the tissue that insulates nerve fibers in the central nervous system, which includes the brain and spinal cord.
There is currently no known cure for multiple sclerosis.
The 52 year old threw more light on the symptoms associated with the health condition during the November 5 episode of the “MeSsy” podcast, which she co-hosts with fellow actress Jamie-Lynn Sigler, who also has MS.
“Everybody has, like, different ways of [the disease] showing up.
“I lay in bed screaming — like, the sharp pains, the ache, that squeezing,” she said.
Applegate also revealed new symptoms she has felt throughout her body.
“I can’t even pick up my phone sometimes because now it’s traveled into my hands, so I’ll, like, try to go get my phone or get my remote to turn on the TV or sometimes, I can’t even hold them. I can’t open bottles now.”
The Married…with Children alum compared getting out of bed in the morning to the feeling of “the floor is lava. The floor is lava.”
“I just lay in bed all the time. I mean, I worked for almost 50 years, so I’m like, I’m kind of okay with it.”
She continued, “I put my feet on the ground and they’re hurting, like, extraordinarily bad to the touch,” said Applegate.
Applegate who was diagnosed with the chronic disease in 2021, mentioned that although her exterior may appear fine, it’s only because people are unaware of what’s happening inside.
Rory Kandel, the owner of Rory’s Bakehouse, who was also present on the episode shared her own experience.
“It feels like I have knives in my stomach,” Kandel said. “Like, I’ll be laying in bed, and I wake up, and I physically can’t turn from side to side.”

Olekanma Favour is a resourceful, self-motivated, and result-driven writer with a passion for crafting compelling narratives and insightful content. She loves tackling complex topics and weaving engaging stories.
When she’s not writing, Olekanma enjoys immersing herself in a good book, exploring new cuisines, and discovering new cultures.
